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Interpretable neural architecture search and transfer learning for understanding CRISPR–Cas9 off-target enzymatic reactions

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Year: 2023
Type: article
Source: Nature Computational Science
DOI: 10.1038/s43588-023-00569-1
Authors: Zijun Zhang, Adam R. Lamson, Michael Shelley, Olga Troyanskaya
Institutions: Cedars-Sinai Medical Center, Flatiron Institute, Courant Institute of Mathematical Sciences, New York University, Princeton University
Language: English

Topic: CRISPR and Genetic Engineering
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: green

Funders: U.S. Department of Health and Human Services, Simons Foundation, National Institute of General Medical Sciences
Awards: lntegration and Visualization of Diverse Biological Data, G360269308, G6340883997
OpenAlex ID: W4377866119
FWCI: 2.221
Cites: 62
Cited by: 25
Related to: 10
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