Year: 2023
Type: article
Study design: Observational Study
Abstract: Excess mortality risk imparted by acute respiratory failure in children is unknown. We determined excess mortality risk associated with mechanically ventilated acute respiratory failure in pediatric sepsis. Novel ICD10-based algorithms were derived and validated to identify a surrogate for acute respiratory distress syndrome to calculate excess mortality risk. Algorithm-identified ARDS was identified with specificity of 96.7% (CI 93.0 - 98.9) and sensitivity of 70.5% (CI 44.0 - 89.7). Excess risk of mortality for ARDS was 24.4% (CI 22.9 - 26.2). Development of ARDS requiring mechanical ventilation imparts modest excess risk of mortality in septic children.
Source: Thorax
Authors: Garrett Keim, Andrew G Percy, Adam S Himebauch, Jesse Y Hsu, Jason D Christie, Nadir Yehya
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Awards: Mentored Patient Oriented Research in Lung Transplantation, Physician Postdoctoral Research Training in Perioperative Medicine (PPRTPM), Pediatric Hospital Epidemiology and Outcomes Research Training Program, The Roles of Pulmonary Hypertension and Right Ventricular Dysfunction in Pediatric Acute Respiratory Distress Syndrome
OpenAlex ID: W4377970795