Distinct T Cell Functional Profiles in Sars-Cov-2 Seropositive and Seronegative Children Associated with Endemic Human Coronavirus Cross-Reactivity
Year: 2023
Type: preprint
Study design: Observational Study
Source: medRxiv
Authors: Ntombi S.B Benede, Marius B. Tincho, Avril Walters, Vennesa Subbiah, Amkele Ngomti, Richard Baguma, Claire Butters, Lina Hahnle, Mathilda Mennen, Sango Skelem, Marguerite Adriaanse, Heidi Facey-Thomas, Christiaan Scott, Jonathan Day, Timothy Spracklen, Strauss van Graan, Sashkia R. Balla, Thandeka Moyo-Gwete, Penny L. Moore, Rae MacGinty, Maresa Botha, Lesley Workman, Marina Johnson, David Goldblatt, Heather Zar, Ntobeko Ntusi, Liesl Zühlke, Kate Webb, Catherine Riou, W Burgers, Roanne S. Keeton
Institutions: University of Cape Town, Institute of Infectious Disease and Molecular Medicine, Red Cross War Memorial Children's Hospital, Groote Schuur Hospital, National Health Laboratory Service, University of the Witwatersrand, National Institute for Communicable Diseases, Centre for the AIDS Programme of Research in South Africa, Wellcome Centre for Infectious Diseases Research in Africa, South African Medical Research Council, University of KwaZulu-Natal, The Francis Crick Institute, University College London
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: Bill and Melinda Gates Foundation, Wellcome Trust, Department of Science and Innovation, South Africa, National Institute for Health and Care Research, National Research Foundation, South African Medical Research Council, Poliomyelitis Research Foundation, Department of Science and Technology, Ministry of Science and Technology, India, National Institutes of Health, Medical Research Council, National Institute of Allergy and Infectious Diseases, European and Developing Countries Clinical Trials Partnership
Awards: Optimising pharmacometric assessment in phase 2 studies of Chagas disease, G1288721568, G2542180245, G2813663117, G3298528487, J. Craig Venter Institute - to use new molecular technologies to elucidate the nasopharyngeal microbiome in GEMS & PERCH sites where factors such as ethnicity, environment, an..., G3685900323, Centre for Infectious Diseases Research in Africa (CIDRI-Africa), G4040994733, Adaptive responses to SARS-CoV-2 variants in the context of hybrid immunity and immune impairment, Contribution of the CD153/CD30 axis to Mycobacterium tuberculosis control in humans, G5522199286, Centre for Infectious Diseases Research in Africa (CIDRI-Africa), G5989569716, G6308935749, G6439542666, Deciphering the immunological signatures of the TB spectrum from infection to disease, G7210099979, G790229736, Characterizing the spectrum of TB and Co-infection with HIV - the role of Th22 cells
OpenAlex ID: W4377986282