Year: 2023
Type: article
Abstract: We report a Brønsted acid catalyzed enantioselective silylation of biaryl diols with an allylsilane as a silicon source. This process enables facile access to enantioenriched biaryl silyl ethers with an axial stereogenicity. A control experiment supports a mechanism proceeding by desymmetrization followed by kinetic resolution.
Source: Synlett
DOI: 10.1055/a-2100-1575
Authors: Benjamin List, Jung Tae Han, Hui Zhou
Institutions: Max-Planck-Institut für Kohlenforschung, Max Planck Society
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
OpenAlex ID: W4378190489