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Fragment-Based Discovery of Azocyclic Alkyl Naphthalenesulfonamides as Keap1-Nrf2 Inhibitors for Acute Lung Injury Treatment

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Year: 2023
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.3c00686
Authors: Jianyu Yan, Yue Li, Li Ding, Ruilin Hou, Chengguo Xing, Chengshi Jiang, Zhenyuan Miao, Chunlin Zhuang
Institutions: Second Military Medical University, University of Jinan, Ningxia Medical University, University of Florida
Language: English

Topic: Genomics, phytochemicals, and oxidative stress
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, National Outstanding Youth Science Fund Project of National Natural Science Foundation of China, Key Research and Development Program of Ningxia, National Key Research and Development Program of China, Shanghai Shuguang Program
Awards: G2247782937, G5288129086, G6365256617, G7886130519, G7889320389
OpenAlex ID: W4378802575
FWCI: 1.506
Cites: 33
Cited by: 20
Related to: 10
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