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A first-in-human, phase 1 study of the SHP2 inhibitor PF-07284892 as monotherapy and in combination with different targeted therapies in oncogene-driven, treatment-resistant solid tumors.

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Year: 2023
Type: conference-abstract
Source: Journal of Clinical Oncology
DOI: 10.1200/jco.2023.41.16_suppl.3020
Authors: Alexander E. Drilon, Melissa Lynne Johnson, Shirish M. Gadgeel, Dale Nepert, Gang Feng, Marzieh Golmakani, Micaela Reddy, Allison Harney, Colleen Oliver, Bethany Mills, Judy Therond, S. Michael Rothenberg, Manish Sharma, Timothy A. Yap
Institutions: Memorial Sloan Kettering Cancer Center, Sarah Cannon, Henry Ford Health, Henry Ford Hospital, Pfizer (United States), The University of Texas MD Anderson Cancer Center
Language: English

Topic: Protein Tyrosine Phosphatases
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funder: Pfizer
OpenAlex ID: W4379283324
Cites:
Cited by: 8
Related to: 10
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