Safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars
Year: 2023
Type: article
Study design: Observational Study
Abstract: Importance: It is necessary to determine whether safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars. Objective: To identify autologous skin tissue cells grafting can reduce facial sunken or flat scars. Design setting and participants: In this retrospective cross-sectional study, a total of 128 patients with scar (exclude pathological scar patients), who were receiving autologous skin tissue cells grafting therapy from January 1, 2016, to December 31, 2019. Interventions: Autologous skin tissue cells grafting. Main outcomes and measures: Changes in scar severity, color changes in the scar area, infection rate and patient satisfaction. Results: A total of 128 patients with scar (89 females [69.5%]; mean [SD] age, 30.6 [13.12] years) received autologous skin tissue cells grafting therapy. SCAR (Scar Cosmesis Assessment and Rating), with scores ranging from 0 (best possible scar) to 15 (worst possible scar). After treatment 12 months, the mean [SD] of SCAR score went down from 9.85 [1.33] to 2.67 [1.21]. No infection was observed during treatment or recovery, and the main drawback after autologous skin tissue cells grafting is that the color recovery time is longer. The patient satisfaction 6 months after treatment was 85.2%, furthermore 12 months after treatment patient satisfaction was 94.7%. Conclusions and relevance: In this study, autologous skin tissue cells grafting was safe and effective to treat facial scars. Therefore, autologous skin tissue cells grafting may be recommended as a reliable treatment for facial scar.
Source: Heliyon
Authors: Tao Liu, Jinxi Chen, Bin Wei, Fangfang Nie, Guanghui Zhu
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,100
Awards: G4967914848, G6294312855, G8087523716
OpenAlex ID: W4379741654