Year: 2023
Type: article
Study design: Observational Study
Abstract: Objective: Pityriasis rosea (PR) is a self-limiting acute rash with unclear etiology and pathogenesis. The cytokine profile of PR is an infrequently investigated field of research. The aim of this study was to assess the level of IL-36 in sera of patients with PR and its possible interrelation with disease severity. Methods: Forty patients with PR were included in this case-control study, and 40 comparable healthy control subjects. Severity was assessed using pityriasis rosea severity score (PRSS) and serum IL-36 was assessed using ELISA. Results: = 0.000). Conclusion: Serum IL-36 could be considered a potential biomarker for pityriasis rosea that correlates with the disease severity.
Source: PubMed Central
Institution: Benha University
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4379769486