PBRM1 and KDM5C cooperate to define high-angiogenesis tumors and increased antiangiogenic response in renal cancer.
Year: 2023
Type: article
Abstract: mutations are common in patients with metastatic ccRCC and likely cooperate increasing tumor angiogenesis and VEGFR-TKI-based antiangiogenic therapy benefit.
Source: PubMed Central
Authors: María Santos, Javier Lanillos, Eduardo Caleiras, Carlos Valdivia, Juan M Roldan-Romero, Nuria Laínez, Javier Puente, Benoit Beuselinck, Stéphane Oudard, Jessica Zucman-Rossi, Paloma Navarro, Mercedes Robledo, Daniel Castellano, Guillermo de Velasco, Jesús García-Donas, Cristina Rodriguez-Antona
Institutions: Spanish National Cancer Research Centre, Complejo Hospitalario de Navarra, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Centro de Investigación Biomédica en Red de Cáncer, Université Paris Cité, Assistance Publique – Hôpitaux de Paris, Hôpital Européen Georges-Pompidou, Inserm, Centre de Recherche des Cordeliers, HM Hospitales, Centre for Biomedical Network Research on Rare Diseases, Hospital Universitario 12 De Octubre
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4379966812