Work

Therapeutic effect of hydrogen and its mechanisms in kidney disease treatment

Year: 2023

Type: review

Abstract: Hydrogen is a simple, colorless, and biologically active small molecule gas that can react with reactive oxygen species. Recent research suggests that hydrogen possesses several biological effects, including antioxidant, anti-inflammatory, and anti-apoptotic effects, while exhibiting an extremely high level of safety. Hydrogen application has shown promise in treating a range of acute and chronic diseases, both benign and malignant. Importantly, an increasing number of clinical studies on hydrogen have demonstrated its efficacy and safety in treating various diseases. This review highlights the beneficial effects of hydrogen in kidney diseases, summarizes potential mechanisms by which hydrogen may act in these diseases, and proposes several promising avenues for future research.

Source: Medical Gas Research

DOI: 10.4103/2045-9912.378880

Authors: Jin Cheng, Minmin Shi, Xuejun Sun, Hongtao Lu

Institutions: Second Military Medical University, Shanghai Jiao Tong University

Language: English

Topic: Hydrogen's biological and therapeutic effects

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: Shanghai Rising-Star Program