Work

Mercury intoxication disrupts tonic signaling in B cells, and may promote autoimmunity due to abnormal phosphorylation of STIM-1 and other autoimmunity risk associated phosphoproteins involved in BCR signaling

Year: 2023

Type: article

Source: Toxicology and Applied Pharmacology

DOI: 10.1016/j.taap.2023.116607

Authors: N.J. Carruthers, C. Guo, R. Gill, P.M. Stemmer, A.J. Rosenspire

Institution: Wayne State University

Language: English

Topic: Heavy Metal Exposure and Toxicity

Subfield: Health, Toxicology and Mutagenesis

Field: Environmental Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Wayne State University, East Carolina University, Brody School of Medicine, National Institutes of Health, NIH Office of the Director, National Cancer Institute, National Institute of Environmental Health Sciences

Awards: Understanding the connection between exposure to mercury, auto-immunity and tolerance in B cells., Center for Urban Responses to Environmental Stressors (CURES), G5044033314, G5857988798, G5967209050, G5978476278, Orbitrap Tribrid Mass Spectrometer for Wayne State Proteomics, G9000145461, CANCER CENTER SUPPORT GRANT

OpenAlex ID: W4381325675

FWCI: 0.325

Cites: 71

Cited by: 3

Related to: 10