FIGURE 5 from Targeting Fatty Acid Reprogramming Suppresses CARM1-expressing Ovarian Cancer
Year: 2023
Type: other
Abstract: CARM1 KO sensitizes cells to saturated FA. Sensitivity of control and CARM1 KO A1847 cells to BSA conjugated palmitate FA determined by colony formation assay (A), which was quantified as dose–response curves (B). C–D, Same as A and B but not control and CARM1-overexpressing CAVO3 cells. E, Expression of cleaved PARP, cleaved Lamin A, CARM1 and a loading control β-actin in control and CARM1 KO A1847 cells treated with or without SCD1 inhibitor CAY10566 and supplemented with 1 mg/mL BSA conjugated oleic acid or BSA control. Data represent mean ± SEM, n = 4 biologically independent experiments.
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4381382650