Chemical Profile and Cytotoxicity Activity of Stem-bark of Anacardium occidentale
Year: 2022
Type: article
Abstract: Column chromatographic fractionation of the methanol and ethyl acetate extracts of the stem-bark of Anacardium occidentale led to the isolation of five compounds (1-5). Their structures were determined by spectroscopic means by comparing spectral data to be β-sitosterol (1), 2,4-dihydroxy acetophenone (2), 1-monolinolein (3), ethyl oleate (4) and β-sitosterol-3-O-β-D-glucopyranoside (5). These compounds were evaluated for cytotoxicity against human cancer cell lines: A549, SCOV3 and rat normal cell line NRK49f. Compounds 2-5 were for the first time isolated from A. occidentale.
Source: Natural Product Sciences
Authors: Shehu Abdullahi, Gowri Ponnapalli Mangala, Mahboob Mohd, Venkata Prabhakar Pitta, Ademola Olatunji Gabriel
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4381663423