Work

Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization

Year: 2023

Type: article

Source: Cell chemical biology

DOI: 10.1016/j.chembiol.2023.06.002

Authors: Martin P. Schwalm, Andreas Krämer, Anja Dölle, Janik Weckesser, Xufen Yu, Jian Jin, Krishna Saxena, Stefan Knapp

Institutions: Goethe University Frankfurt, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, German Cancer Research Center, Deutsches Konsortium für Translationale Krebsforschung

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W4381850174

FWCI: 7.699

Cites: 38

Cited by: 103

Related to: 10