Year: 2023
Type: review
Abstract: DNA-mediated programming is emerging as an effective technology that enables controlled dynamic assembly/disassembly of inorganic nanocrystals (NC) with precise numbers and spatial locations for biomedical imaging applications. In this review, we will begin with a brief overview of the rules of NC dynamic assembly driven by DNA ligands, and the research progress on the relationship between NC assembly modes and their biomedical imaging performance. Then, we will give examples on how the driven program is designed by different interactions through the configuration switching of DNA-NC conjugates for biomedical applications. Finally, we will conclude with the current challenges and future perspectives of this emerging field. Hopefully, this review will deepen our knowledge on the DNA-guided precise assembly of NCs, which may further inspire the future development of smart chemical imaging devices and high-performance biomedical imaging probes.
Source: Chemical & Biomedical Imaging
DOI: 10.1021/cbmi.3c00028
Authors: Shengfei Yang, Yuqi Wang, Qiyue Wang, Fangyuan Li, Daishun Ling
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
Funders: Innovative Research Team of High-level Local University in Shanghai, Shanghai Science and Technology Development Foundation, National Natural Science Foundation of China, Ministry of Education of the People's Republic of China, Chinese Academy of Sciences, Ministry of Science and Technology of the People's Republic of China, Science and Technology Commission of Shanghai Municipality, Natural Science Foundation of Zhejiang Province
OpenAlex ID: W4382020275