Work

Decoding a ribosome uncertainty

Year: 2023

Type: article

Abstract: The ribosome is among the most ancient macromolecular complexes. Throughout evolution, the function of the ribosome has remained essential and conserved: the decoding of an mRNA template with tRNA-linked amino acids, to synthesize a protein. In a recent study, Holm et al. capture evolutionary distinctions in the structure and kinetics of 'mRNA decoding' by the human ribosome.

Source: Trends in Genetics

DOI: 10.1016/j.tig.2023.06.001

Authors: Olivier Duss, Rainer Nikolay, Matthew L. Kraushar

Institutions: European Molecular Biology Laboratory, European Molecular Biology Laboratory, Max Planck Institute for Molecular Genetics

Language: English

Topic: RNA and protein synthesis mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $6,830

OpenAlex ID: W4382051830

FWCI: 0.089

Cites: 11

Cited by: 1

Related to: 10