Work

Synthesis of Naturally Racemic Marilines B & C through Multicomponent Reactions Involving ortho-Quinone Methides and Various Nitrogen Nucleophiles

Year: 2023

Type: article

Abstract: Herein, we report the first total synthesis of (±)-marilines B and C, as well as a failed approach to (±)-mariline A, by using our recently developed multicomponent reaction method, which involves the interception of ortho-quinone methides with various nitrogen nucleophiles to allow easy assembly of various benzylic amine cores with diverse substituents.

Source: Synthesis

DOI: 10.1055/s-0041-1738443

Authors: Thomas R. R. Pettus, Yuk Fai Wong

Language: English

Topic: Cyclization and Aryne Chemistry

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: University of California, Santa Barbara

OpenAlex ID: W4382363616

FWCI: 0.103

Cites: 22

Cited by: 1

Related to: 10