Year: 2023
Type: article
Abstract: On September 25 and 26, 2021, the Alzheimer's Association hosted the first meeting focused on people with early-onset Alzheimer's disease (EOAD)-sometimes referred to as younger onset Alzheimer's disease (AD). Though a diagnosis of AD can be devastating at any age, those with a younger onset-defined as symptoms developing prior to 65 years of age-face unique challenges. EOAD occurs when people are in the prime of their lives, often with multiple responsibilities including careers, community activities, and raising children and caring for older family members. These challenges warrant special consideration and study, yet people with EOAD are often excluded from AD research because of their atypical age of onset. To help fill this gap, we designed and launched the Longitudinal Early-Onset Alzheimer's Disease Study (LEADS) to enroll and follow 500 people with EOAD from > 15 sites in the United States, which the National Institute on Aging funded in 2018. The September 2021 meeting was designed to inform people with EOAD and their family members and caregivers about the latest research on the biology of EOAD, treatments in the pipeline, practical considerations about legal and financial arrangements for families, and the support networks available to them. More than 217 registrants attended.
Source: Alzheimer s & Dementia
DOI: 10.1002/alz.13353
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Awards: G1024368718, G1048051091, G1171648585, G1224480130, G1269895679, G1309605592, Indiana Alzheimer Disease Center, G1369195717, G1531775036, G1734698810, G1753564228, G1859882300, G2190936067, G2632195949, Early Onset AD Consortium - the LEAD Study (LEADS), G343469054, G3703765782, G371566797, G3727582191, G468709790, The Role of Copy Number Variants and Epigenetic Dysregulation in Early Onset Alzheimer’s Disease (EOAD), G504619356, G5056789898, G535282987, LEADing Diverse Recruitment at Mayo Clinic Florida, G6246463580, G6250057130, G639043084, G6425121803, Indiana University LEADS Diversity Recruitment Supplement, G6876577119, G7176475171, Promoting Diverse Perspectives: Addressing Health Disparities Related to Alzheimer's and other Dementias, G76412088, LEADS Diversity Recruitment and Community Engagement in Rhode Island, G816726602, G8924848700, Alzheimer's Disease Research Center, Johns Hopkins Alzheimer's Disease Research Center, Arizona Alzheimer's Disease Research Center, Stanford Alzheimer's Disease Research Center, Penn Alzheimer's Disease Research Center (ADRC), National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD), Massachusetts Alzheimer's Disease Research Center (MADRC), Goizueta Alzheimer's Disease Research Center
OpenAlex ID: W4382653921