Work

Preserved endothelium-independent vascular function with aging in men and women: evidence from the peripheral and cerebral vasculature

Year: 2023

Type: article

Abstract: To confidently explain peripheral and cerebral vascular dysfunction, it is essential to have a clear understanding of the endothelial-independent function of VSMCs across age and sex. By assessing endothelium-independent dilation using sublingual nitroglycerin, endothelial-independent VSMC function in the periphery (popliteal artery), and in the cerebral circulation (middle cerebral artery), was not different due to age or sex. In addition, endothelial-independent VSMC function in one of these vascular beds is not reflected in the other.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00571.2022