A moving target: impacts of lowering viral load suppression cutpoints on progress towards HIV epidemic control goals
Year: 2023
Type: article
Abstract: Redefining viral load suppression (VLS) using lower cutpoints could impact progress towards the UNAIDS 95-95-95 targets. We assessed impacts of lowering the VLS cutpoint on achieving the 95-95-95 VLS target in the Rakai Community Cohort Study. Population VLS fell from 86% to 84% and 76%, respectively, after lowering VLS cutpoints from <1,000 to <200 and <50 copies/mL. The fraction of viremic persons increased by 17% after lowering the VLS cutpoint from <1,000 to <200 copies/mL.
Source: AIDS
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: Division of Intramural Research, National Institute of Allergy and Infectious Diseases, Johns Hopkins University, U.S. President’s Emergency Plan for AIDS Relief, National Institutes of Health, Centers for Disease Control and Prevention, National Institute of Mental Health, National Institute of Allergy and Infectious Diseases, NHLBI Division of Intramural Research
Awards: Understanding HIV risk and service use in hotspot Ugandan fishing communities, G1230754110, G201659893, G2672645366, G3175806859, The role of penile bacteria and inflammation in HIV susceptibility; Rakai, Uganda, PROVISION OF COMPREHENSIVE HIV/AIDS SERVICES AND DEVELOPING NATIONAL CAPACITY TO, G462800458, G6002302656, Long-term impact of universal treatment and dolutegravir on population HIV virologic and incidence outcomes in Africa: The LONGVIEW Study, G6778109039, G890594366, G8971497436, Implementation Research to Optimize ART Delivery for Adolescents and Young Adults Living with HIV, Johns Hopkins HIV Epidemiology and Prevention Sciences Training Program, G919554216, G94663013
OpenAlex ID: W4382918697