Multimodal Detection and Targeting of Biopsy-Proven Myocardial Inflammation in Genetic Cardiomyopathies
Year: 2023
Type: article
Study design: Observational Study
Abstract: The authors present a clinical report focused on the overlap between myocarditis and genetic cardiomyopathies of the dilated and arrhythmogenic spectrum. Our cohort was composed of 25 patients undergoing extensive baseline characterization and prospective reassessment by a dedicated multidisciplinary disease unit during a median follow-up of 69 months. We showed that the use of multimodal imaging allowed both discrimination of specific genotypes and identification of myocardial inflammation proven using endomyocardial biopsy. In addition, we showed that the use of immunomodulatory therapy was beneficial for most patients.
Authors: Giovanni Peretto, Giacomo De Luca, Andrea Villatore, Chiara Di Resta, Simone Sala, Anna Palmisano, Davide Vignale, Corrado Campochiaro, Davide Lazzeroni, Monica De Gaspari, Stefania Rizzo, Elena Busnardo, Paola Ferro, Luigi Gianolli, Cristina Basso, Lorenzo Dagna, Antonio Esposito, Sara Benedetti, Paolo Della Bella
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $4,530
OpenAlex ID: W4383216466