Work

Long-term changes in heart rate and electrical remodeling contribute to alternans formation in heart failure: a patient-specific in silico study

Year: 2023

Type: article

Abstract: Using patient-specific data, we show that both the changes in heart rate and electrical remodeling associated with chronic heart failure influence the formation of proarrhythmic alternans in the heart.

Source: American Journal of Physiology-Heart and Circulatory Physiology

DOI: 10.1152/ajpheart.00220.2023

Authors: Vrishti M. Phadumdeo, Brianna L. Mallare, Thomas J. Hund, Seth H. Weinberg

Institution: The Ohio State University

Language: English

Topic: Cardiac electrophysiology and arrhythmias

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute

Awards: Signaling in Inherited and Acquired Sodium Channel Gain of Function, Distinct Ion Channel Pools and Intercalated Disk Nanoscale Structure Regulate Cardiac Conduction

OpenAlex ID: W4383480589

FWCI: 0.526

Cites: 67

Cited by: 3

Related to: 10