Gemini Amphiphiles: Robust Cytosolic Delivery of Therapeutic Biomacromolecules through Non-Endocytic Translocation Pathways
Year: 2023
Type: other
Abstract: ADVERTISEMENT RETURN TO ARTICLES ASAPPREVFirst ReactionsNEXTGemini Amphiphiles: Robust Cytosolic Delivery of Therapeutic Biomacromolecules through Non-Endocytic Translocation PathwaysGemini amphiphile (GA)-based vehicles represent a promising platform for the intracellular delivery of a large palette of macromolecular therapeutics.Yu ZhaoYu ZhaoDepartment of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155, United StatesMore by Yu Zhao, Douglas WichDouglas WichDepartment of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155, United StatesMore by Douglas Wich, and Qiaobing Xu*Qiaobing XuDepartment of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155, United States*Email: [email protected]More by Qiaobing Xuhttps://orcid.org/0000-0001-7323-7795Cite this: ACS Cent. Sci. 2023, XXXX, XXX, XXX-XXXPublication Date (Web):July 7, 2023Publication History Published online7 July 2023https://doi.org/10.1021/acscentsci.3c00793Published 2023 by American Chemical SocietyRIGHTS & PERMISSIONSACS AuthorChoiceCC: Creative CommonsBY: Credit must be given to the creatorArticle Views-Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-AlertscloseSUBJECTS:Alkyls,Cancer therapy,Drug delivery,Lipids,Membranes Get e-Alerts
Source: ACS Central Science
Authors: Yu Zhao, Douglas Wich, Qiaobing Xu
Institution: Tufts University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4383499711