Work

Deciphering the polycistronic nature of Mycobacterium tuberculosis lipoproteins of unknown functions

Year: 2023

Type: preprint

Abstract: Mycobacterium tuberculosis , the causative agent of human tuberculosis, encodes 116 lipoproteins, from which 48 have no demonstrated or predicted function. In this study, we demonstrated that six genes of these lipoproteins of unknown function are encoded in transcriptional units together with genes with experimentally verified functions or that encode conserved functional domains. We assigned predicted functions to LpqT (Rv1016c), LppE (1881c), LppO (Rv2290), LprE (Rv1252c) and LpqF (Rv3593).

Source: bioRxiv (Cold Spring Harbor Laboratory)

DOI: 10.1101/2023.07.16.549196

Authors: Blanco, Fabiana Bigi

Institution: National Agricultural Technology Institute

Language: English

Topic: Tuberculosis Research and Epidemiology

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4384526054

Cites: 7

Cited by:

Related to: 10