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Synthesis and characterization of H-cardanol incorporated C(3)-aminoisoindolinones

Year: 2023

Type: article

Abstract: A facile and high-yielding synthesis of the hydrophobic and the hexane soluble H-cardanol incorporated C(3)-aminoisoindolinones has been successfully achieved. Additionally, the synthesis of the H-cardanol embedded tetracyclic C(3)-aminoisoindolinones has also been successfully achieved. The H‑cardanol incorporated isoindolinones are low melting, lipophilic solids and readily soluble in hydrocarbon solvents - a property useful for topical administration of medicinal drugs. The UV-Vis spectra of the C(3)-aminoisoindolinones with two H-cardanol units do not indicate an intramolecular association between the two aromatic rings.

Source: Indian Journal of Chemistry

DOI: 10.56042/ijc.v62i7.3737

Authors: H Surya Prakash Rao, Prabhakaran J

Institution: Pondicherry University

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funders: Department of Science and Technology, Ministry of Science and Technology, India, Northwest Fisheries Science Center

OpenAlex ID: W4384928987

FWCI:

Cites: 2

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Related to: 10