Work

Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities

Year: 2023

Type: article

Source: Nature Structural & Molecular Biology

DOI: 10.1038/s41594-023-01041-4

Authors: Yuxiang Zhang, David Remillard, Ugoma Onubogu, Barbara Karakyriakou, Joshua N. Asiaban, Anissa R. Ramos, Kirsten Bowland, Timothy R. Bishop, Paige A. Barta, Stephanie Nance, Adam D. Durbin, Christopher J. Ott, Michalina Janiszewska, Benjamin F. Cravatt, Michael A. Erb

Institutions: Scripps Research Institute, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Massachusetts General Hospital, St. Jude Children's Research Hospital, Broad Institute, Harvard University

Language: English

Topic: Histone Deacetylase Inhibitors Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Ono Pharma Foundation, National Institutes of Health, National Cancer Institute

Awards: Targeting EP300, a selective dependency in neuroblastoma, Targeting crotonyl-lysine chromatin readers to disrupt pathogenic gene expression in leukemia, G4681055516

OpenAlex ID: W4385197455

FWCI: 2.532

Cites: 103

Cited by: 35

Related to: 10