Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering
Work
Year: 2023
Type: article
Abstract: Chimeric antigen receptor (CAR) engineering of natural killer (NK) cells is promising, with early-phase clinical studies showing encouraging responses. However, the transcriptional signatures that con... more
Source: Science Advances
Institutions The University of Texas MD Anderson Cancer Center, Broad Institute, Dana-Farber Cancer Institute, Harvard University, Rice University +2 more
Cites: 47
Cited by: 52
Related to: 10
FWCI: 12.82
Citation percentile (by year/subfield): 99.99
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
APC paid (est): $4,500