Supplementary Figure 3 from The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Figure 3. A. Western blot analysis results showing the expression of CELSR3 following CELSR3 or GFP knock-out in the indicated NEPC PDO xenograft tumors for each of the mice (m) that were part of the experiment as described for Figure 3. B. Graphic representation of the percentage of orthotopic NEPC PDO xenograft clones that were engineered with either sgCELSR3 or sgGFP CRISPR-Cas9 that formed macro-metastatic lesions at the indicated region of the mice. C. and D. H&E and IHC staining of the indicated markers.
Authors: Lucie Van Emmenis, Sheng-Yu Ku, Kaitlyn Gayvert, Jonathan R. Branch, Nicholas J. Brady, Subhasree Basu, Michael Russell, Joanna Cyrta, Aram Vosoughi, Verena Sailer, Hussein Alnajar, Etienne Dardenne, Elena Koumis, Loredana Puca, Brian D. Robinson, Michael D. Feldkamp, Annmarie Winkis, Nathan Majewski, Brent Rupnow, Marco M. Gottardis, Olivier Elemento, Mark A. Rubin, Himisha Beltran, David S. Rickman
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4385580787