Supplementary Figure S5 from Multiomic Mapping of Acquired Chromosome 1 Copy-Number and Structural Variants to Identify Therapeutic Vulnerabilities in Multiple Myeloma
Year: 2023
Type: supplementary-materials
Abstract: Hi-C interaction and TAD map of CT1, TI1, D7 regions. The chromatin confirmation of the region encompassing CT1, TI1, and D7 across the 3 HMCLs (U266, RPMI8226, and KMS11) and PC for comparison. The region shows significant variability in the TAD strucure at the TENT5C locus across all samples in comparision to PC which could explain its dysregulation
Authors: Eileen M. Boyle, Patrick Blaney, James H. Stoeckle, Yubao Wang, Hussein Ghamlouch, Dylan Gagler, Marc Braunstein, Louis Williams, Avital Tenenbaum, Ariel Siegel, Xiaoyi Chen, Gaurav Varma, Jason Avigan, Alexander Li, Monica Jinsi, David Kaminetzsky, Arnaldo Arbini, Lydia Montes, Jill Corre, Even H. Rustad, Ola Landgren, Francesco Maura, Brian A. Walker, Michael Bauer, Benedetto Bruno, Aristotelis Tsirigos, Faith E. Davies, Gareth J. Morgan
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4385665891
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