Work

Build instructions for a long term behavioural enclosure for measuring motivational switching in mice

Year: 2023

Type: other

Abstract: Switching between motivated behaviours, such as feeding, drinking and socializing, is important for survival in a dynamic, social environment. Inflexible repetitive behaviours are a hallmark of many neuropsychiatric disorders. Studies of the neural mechanisms underlying motivated behaviours, i.e., drives, seldom focus on switching between them. This is partly due to a lack of appropriate behavioural measurement systems. In this study, we build and test a device for measuring motivational switching in mice, the Switchmaze. We present build instructions using affordable off-the-shelf components, and openly accessible acquisition and analysis scripts.

Source: ResearchEquals

DOI: 10.53962/mn5r-7ekh

Authors: Clara Hartmann, Vinicius Pereira Mateus Borges, Yves Thönnes, Mahesh Karnani

Institution: Vrije Universiteit Amsterdam

Language: English

Topic: Neurotransmitter Receptor Influence on Behavior

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: hybrid

Funders: Vrije Universiteit Amsterdam, Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Award: BRAINSCAPES: A Roadmap from Neurogenetics to Neurobiology

OpenAlex ID: W4385719742

Cites: 27

Cited by: 2

Related to: 10