Work

Responsiveness, Sensitivity and Clinical Utility of Timing-Related Speech Biomarkers for Remote Monitoring of ALS Disease Progression

Year: 2023

Type: conference-paper

Abstract: = 94). We further evaluated the sensitivity of speech metrics in tracking disease progression in pALS while their ALSFRS-R speech score remained unchanged at 3 out of a total possible score of 4. We observed that timing-related speech metrics showed significant longitudinal changes even after accounting for learning effects. The findings of this study have the potential to inform disease prognosis and functional outcomes of clinical trials.

Source: Interspeech (USB)

DOI: 10.21437/interspeech.2023-2002

Authors: Hardik Kothare, Michael Neumann, Jackson Liscombe, Jordan Green, Vikram Ramanarayanan

Institutions: Nodality (United States), MGH Institute of Health Professions, Massachusetts General Hospital, University of California, San Francisco

Language: English

Topic: Voice and Speech Disorders

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute on Deafness and Other Communication Disorders