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Supplementary Fig. 3 from MEK Inhibition Sensitizes Pancreatic Cancer to STING Agonism by Tumor Cell–intrinsic Amplification of Type I IFN Signaling

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Fig. 3 MEK inhibition amplifies STING-induced transcription of IFNB1, IL-6, and TNFA in multiple PDAC cell lines.

DOI: 10.1158/1078-0432.23952468

Authors: Razmik Ghukasyan, Keke Liang, Kevin Chau, Luyi Li, Charlotte Chan, Evan R. Abt, Thuc Le, Joon Y. Park, Nanping Wu, Alykhan Premji, Robert Damoiseaux, Tony Luu, Amanda Labora, Khalid Rashid, Jason M. Link, Caius G. Radu, Timothy R. Donahue

Language: English

Topic: interferon and immune responses

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4385836580

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