The MYTHS of De novo Crohn's Disease After Restorative Proctocolectomy with Ileal Pouch-anal Anastomosis for Ulcerative Colitis.
Year: 2020
Type: article
Abstract: Background: Crohn's after IPAA can be picked up in endoscopy biopsy before surgery. Aim: Crohn's disease subsequent to IPAA surgery for ulcerative colitis. Methods: CD was established clinically and histologically based on inflammation of afferent limb(s) or perianal disease. The search excluded non-English language and non-human studies as well as editorials. Results: CD diagnosis depended on either inflammation in the mucosa involving the small intestine proximal to the ileal pouch any time after IPAA surgery and/or when perianal complications developed after closure of a temporary diverting loop ileostomy. Successful management is facilitated by co-operation within a multidisciplinary team of gastroenterologists and colorectal surgeons and closely involving the patient in therapeutic decisions. Awareness of symptoms leads to timely consultation, diagnosis, treatment and restoration of intestinal continuity. Conclusion: CD. A successful management is facilitated by a triad cooperation between gastroenterologists, colorectal surgeons and the patient.
Source: PubMed
Authors: S D James, A T Hawkins, J W Um, B R Ballard, D T Smoot, A E M'Koma
Language: English
Topic: Inflammatory Bowel Disease
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
Awards: MMC and VICC: Partners in Eliminating Cancer Disparities, MMC and VICC: Partners in Eliminating Cancer Disparities, Meharry Clinical and Translational Research Center (MeTRC), Differentiating Ulcerative Colitis and Crohns Colitis Through Proteomic Patterns, The Vanderbilt Institute for Clinical and Translational Research (VICTR) UL1, The Vanderbilt Institute for Clinical and Translational Research (VICTR), Endowment for Health Disparities Research, The RCMI Program in Health Disparities Research at Meharry Medical College
OpenAlex ID: W4385850503