Reply to: Fluid signal suppression characteristics of 3D-FLAIR with a T2 selective inversion pulse in the skull base
Year: 2023
Type: letter
Abstract: First, we would like to thank Dr. Naganawa and his colleagues for their interest in our article. We are happy to address their concerns regarding our article 1 . Their main concern is that the signals we detected in the ventral region represent artifacts rather than lymphatic signals 2 . In the first revision of our manuscript, we detailed the effects of TR, TE, and TI variation in our MR technique on signals measured in a healthy volunteer. Unfortunately, we removed these data from the manuscript in later drafts after including the results of our phantom study. Our study used a 3D-FLAIR technique with a T2-selective inversion pulse. For comparison, Dr. Naganawa presented four different 3D-FLAIR techniques: T2-selective inversion pulse, T2-preparation pulses, conventional inversion pulse similar to our techniques, and conventional inversion using longer repetition time of 8000 (TR/TE/TI: 8000/387/2370) 2 . We will only discuss the first 3, as the fourth technique uses parameters significantly different from those we used (TR/TE/TI: 5000/387/1800).
Source: Nature Communications
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $6,290
OpenAlex ID: W4385874470