Work

AltitudeOmics: effects of 16 days acclimatization to hypobaric hypoxia on muscle oxygen extraction during incremental exercise

Year: 2023

Type: article

Abstract: During incremental exercise muscle deoxyhemoglobin (HHb) and oxygen consumption (V̇o2) both increase linearly, and the slope of their relationship is an indirect index of local muscle O2 extraction. The latter was assessed at sea level, in acute and during chronic exposure to 5,260 m. The demonstrated presence of a muscle O2 extraction reserve during chronic exposure is coherent with previous studies indicating both limited muscle oxidative capacity and decrease in motor drive.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00100.2023

Authors: Nicolas Bourdillon, Andrew W. Subudhi, Jui-Lin Fan, Oghenero Evero, Jonathan E. Elliott, Andrew T. Lovering, Robert C. Roach, Bengt Kayser

Institutions: University of Lausanne, University of Colorado Colorado Springs, University of Auckland, University of Colorado Anschutz, University of Oregon

Language: English

Topic: High Altitude and Hypoxia

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Defense, National Institutes of Health, National Center for Advancing Translational Sciences

Awards: Colorado Clinical and Translational Science Institute (UL1), PREDICTION OF SUSCEPTIBILITY TO ACUTE MOUNTAIN SICKNESS USING HYPOXIA-INDUCED INTRAPULMONARY ARTERIOVENOUS SHUNT AND INTRACARDIAC SHUNT FRACTIONS, G6423879735

OpenAlex ID: W4385897491

FWCI: 0.994

Cites: 48

Cited by: 6

Related to: 10