Work

Probable Olanzapine-Related Idiopathic Intracranial Hypertension in an Adolescent with First-Episode Psychosis

Year: 2025

Type: article

Abstract: Pseudotumor cerebri or idiopathic intracranial hypertension (IIH) secondary to psychotropic drugs is a very rare occurrence. Lithium is typically the culprit agent. Here, authors report on an interesting case of an adolescent with early-onset schizophrenia that develops a reversible IIH putatively related to olanzapine-induced weight gain. This is followed by discussion of purported pharmacodynamic mechanisms and brief review of literature. Clinicians should be cognizant to this serious complication given the propensity of the majority of atypical antipsychotics to induce significant weight gain especially in younger population.

Source: Psychopharmacology Bulletin

DOI: 10.64719/pb.4470

Authors: Ahmed Naguy, Camellia Naguy, Sanaa Sabir

Language: English

Topic: Cerebral Venous Sinus Thrombosis

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4386019946