Work

Long-term risk for atrial and ventricular arrhythmias: a cardinal manifestation of ‘the epileptic heart’

Year: 2023
Type: editorial
Abstract: Conceptual framework of the link between chronic epilepsy and development of an ‘epileptic heart’ condition due to cardiotoxic effects of catecholamines, repeated hypoxaemia, with increased cardiac electrical instability manifest as T-wave alternans, a repeating ABAB beat-to-beat pattern in the ST-segment and T wave of the ECG, and atrial and ventricular arrhythmias.1 Certain antiseizure medications (ASMs) with sodium channel-blocking properties and enzyme-inducing actions can promote both proarrhythmia and hyperlipidaemia.2 The ECG tracings were obtained from a case report of a 51-year-old woman admitted to the epilepsy monitoring unit for video-EEG monitoring who developed ventricular fibrillation following right temporal lobe seizure that required electrical defibrillation.3
Language: English
Field: Medicine
Open Access status: bronze
OpenAlex ID: W4386084848
Cites: 16
Cited by: 4
Related to: 10