Work

High-intensity aerobic, but not resistance or combined, exercise training improves both cardiometabolic health and skeletal muscle mitochondrial dynamics

Year: 2023

Type: article

Abstract: We assessed the effects of 12 wk of supervised high-intensity interval training (HIIT), resistance training, and combined training (CT) on skeletal muscle mitochondrial abundance and markers of fission and fusion. HIIT increased mitochondrial area and size and promoted protein changes indicative of increased mitochondrial fusion, whereas lessor effects were observed after CT and no changes were observed after RT. Furthermore, increased mitochondrial area and size after HIIT associated with improved mitochondrial respiration, cardiorespiratory fitness, and insulin sensitivity.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00405.2023

Authors: Gregory N. Ruegsegger, Mark W. Pataky, Suvyaktha Simha, Matthew M. Robinson, Katherine A. Klaus, K. Sreekumaran Nair

Institutions: Mayo Clinic, University of Wisconsin–River Falls, Oregon State University

Language: English

Topic: Cardiovascular and exercise physiology

Subfield: Complementary and alternative medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green