Supplementary Figures S1-S7 from A Novel Type of Monocytic Leukemia Stem Cell Revealed by the Clinical Use of Venetoclax-Based Therapy
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Fig. 1: Immunophenotyping and WES analysis of primary AML specimens. Supplementary Fig. 2: Immunophenotyping of engrafted cells in PDX. Supplementary Fig. 3: WES analysis and remission duration of VEN/AZA relapsed AML patients. Supplementary Fig. 4: CITE-seq data analysis. Supplementary Fig. 5: Sorting strategies for determining m-LSC immunophenotype and expression of various LSC markers in m-LSCs. Supplementary Fig. 6: Molecular properties and targeting of m-LSCs in vitro and in vivo. Supplementary Fig. 7: M5 but not M4 patients showing significantly higher refractory rate to VEN/AZA therapy.
Authors: Shanshan Pei, Ian T. Shelton, Austin E. Gillen, Brett M. Stevens, Maura Gasparetto, Yanan Wang, Lina Liu, Jun Liu, Tonya M. Brunetti, Krysta Engel, Sarah Staggs, William Showers, Anagha Inguva Sheth, Maria L. Amaya, Mohammad Minhajuddin, Amanda Winters, Sweta B. Patel, Hunter Tolison, Anna E. Krug, Tracy N. Young, Jeffrey Schowinsky, Christine M. McMahon, Clayton A. Smith, Daniel A. Pollyea, Craig T. Jordan
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4386469911