Work

Cutaneous angiosarcoma of the scalp in a pediatric patient with xeroderma pigmentosum

Year: 2023

Type: article

Abstract: Xeroderma pigmentosum (XP) is a rare, DNA repair defect syndrome that presents with significant sensitivity to UV exposure. Patients with XP have significantly increased risk of cutaneous tumors, specifically nonmelanoma and melanoma skin cancers.1,2 Cutaneous angiosarcoma is a rare, aggressive, vascular tumor that typically presents in sites of prior radiation or chronic UV exposure.3 Angiosarcoma in patients with XP presents a treatment conundrum as 1 of the main treatment approaches to angiosarcoma is radiation therapy, whereby the ionizing radiation poses a risk for further morbidity.

Source: JAAD Case Reports

DOI: 10.1016/j.jdcr.2023.08.039

Authors: Valeria S. Oliver-García, Kevin J. Moore, Thomas Denize, Mai P. Hoang, Victor A. Neel, Shadmehr Demehri

Institutions: Harvard University, Massachusetts General Hospital

Language: English

Topic: Vascular Tumors and Angiosarcomas

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $675