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Supplementary Figure S1 from A Druggable FOXA1-Glucocorticoid Receptor Transcriptional Axis Drives Tumor Growth in a Subset of Non-Small Cell Lung Cancer

Year: 2023

Type: supplementary-materials

Abstract: Supplemental figure S1 data panels and legend accompanying main body figure 2. Supplementary Figure S1 shows GR is the top-ranked interacting protein of FOXA1 in FOXA1-dependent NSCLC cell lines models. Additionally, FOXA1-dependent, but not FOXA1-independent NSCLC cells depend on GR for sustained proliferation.

DOI: 10.1158/2767-9764.24101048

Authors: M. Dorso, Payal T. Patel, Aleksandr Pankov, Jacob A. Boyer, Rajesh K. Soni, Isabella S. Del Priore, Omar Hayatt, Amanda Kulick, Connor J. Hagen, Elisa de Stanchina, Melissa R. Junttila, Anneleen Daemen, Lori S. Friedman, Ronald C. Hendrickson, Sarat Chandarlapaty

Language: English

Topic: Estrogen and related hormone effects

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4386526139

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