Work

Incorporating Uremic Solute-mediated Inhibition of OAT1/3 Improves PBPK Prediction of Tenofovir Renal and Systemic Disposition in Patients with Severe Kidney Disease

Year: 2023

Type: article

Source: Pharmaceutical Research

DOI: 10.1007/s11095-023-03594-x

Authors: Shih-Yu Chang, Weize Huang, Alenka Chapron, Antonio J. López Quiñones, Joanne Wang, Nina Isoherranen, Danny D. Shen, Edward J. Kelly, Jonathan Himmelfarb, Catherine K. Yeung

Institutions: University of Washington, Janssen Research & Development (United States), Genentech, Revolution Medicines (United States)

Language: English

Topic: Drug Transport and Resistance Mechanisms

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: University of Washington, Northwest Kidney Centers, National Institutes of Health, National Institute on Drug Abuse, National Institute of General Medical Sciences

Awards: G4980552517, Pharmacology of Drugs of Abuse During Pregnancy, G9000075271

OpenAlex ID: W4386698706

FWCI: 0.825

Cites: 45

Cited by: 8

Related to: 10