Work

Vascularized Hepatocellular Carcinoma on a Chip to Control Chemoresistance through Cirrhosis, Inflammation and Metabolic Activity

Year: 2023

Type: article

Abstract: Patient-Specific Treatment In article 2200403, Alican Özkan, and co-workers created a novel vascularized hepatocellular carcinoma on a chip (HCCoC) composed of tunable collagen and four main liver-specific cells, which serves as a translational testing tool. HCCoC is used to assess vascular transport regulation and efficacy of therapeutics delivered with embolization and systematic methods during the cancer progression.

Source: Small Structures

DOI: 10.1002/sstr.202370024

Authors: Alican Özkan, Danielle L. Stolley, Erik N. K. Cressman, Matthew McMillin, Thomas E. Yankeelov, Marissa Nichole Rylander

Institutions: The University of Texas at Austin, The University of Texas MD Anderson Cancer Center, Central Texas Veterans Health Care System

Language: English

Topic: 3D Printing in Biomedical Research

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,250