Figure 5 from Integrated Multimodal Analyses of DNA Damage Response and Immune Markers as Predictors of Response in Metastatic Triple-Negative Breast Cancer in the TNT Trial (NCT00532727)
Year: 2023
Type: other
Abstract: Results of a novel clustering. A, Response rates by novel clusters and treatment groups. P values are presented from Fisher exact tests. Clusters 4 and 6 are not shown due to small numbers. B, Heatmap showing biological features of each novel cluster. PGA, percentage of genome altered; SI, Shannon diversity index; NtAI, number of telomeric allelic imbalances; AiCna, allelic imbalanced CNA; AbCna, allelic balanced CNA; CnLOH, copy number neutral loss of heterozygosity.
Authors: Holly Tovey, Orsolya Sipos, Joel S. Parker, Katherine A. Hoadley, Jelmar Quist, Sarah Kernaghan, Lucy Kilburn, Roberto Salgado, Sherene Loi, Richard D. Kennedy, Ioannis Roxanis, Patrycja Gazinska, Sarah E. Pinder, Judith Bliss, Charles M. Perou, Syed Haider, Anita Grigoriadis, Andrew Tutt, Maggie Chon U. Cheang
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4386778143