Orphan quality control shapes network dynamics and gene expression
Year: 2023
Type: article
Abstract: (Cell 186, 3460–3475.e1–e23; August 3, 2023) In the originally published version of this article, due to a copy-paste error, Figure 1B inadvertently showed the blot for MYC instead of BUBR1. This has since been corrected online. The authors regret this error. Figure 1BUBR5 binds transcriptional regulators with connections to c-MYC (Corrected)View Large Image Figure ViewerDownload Hi-res image Download (PPT) Orphan quality control shapes network dynamics and gene expressionMark et al.CellJuly 20, 2023In BriefCells use orphan quality control to constantly degrade unpaired transcription factor subunits and, thereby, establish dynamic protein interaction networks that drive accurate gene expression and cell fate determination. Full-Text PDF Open Access
Source: Cell
Authors: Kevin G. Mark, SriDurgaDevi Kolla, Jacob D. Aguirre, Danielle M. Garshott, Stefan Schmitt, Diane L. Haakonsen, Christina Xu, Lukas Kater, Georg Kempf, Brenda Martínez-González, David Akopian, Stephanie K. See, Nicolas H. Thomä, Michael Rapé
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $10,100
OpenAlex ID: W4386789126