Work

Lateral septum modulates cortical state to tune responsivity to threat stimuli

Year: 2023

Type: article

Abstract: (Cell Reports 41, 111521; October 25, 2022) Following an internal review at Boston Children’s Hospital, Sarah Jan Stankowicz has been included as an author on this paper to reflect her contribution (pilot pupillometry and reward conditioning experiments). The author list and the author contributions of the online article have now been updated. The remaining parts of the paper remain unchanged. All co-authors have approved the changes. The authors regret this error. Lateral septum modulates cortical state to tune responsivity to threat stimuliHashimoto et al.Cell ReportsOctober 25, 2022In BriefUsing in vivo neural activity recording, optogenetics, and viral-mediated transneuronal anterograde tracing, Hashimoto et al. find that, rather than simply gating behavior, the lateral septum modulates cortical state and responsivity to sensory stimuli to promote preparatory defensive behavioral states associated with heightened reactivity to threat-related cues. Full-Text PDF Open Access

Source: Cell Reports

DOI: 10.1016/j.celrep.2023.113062