Year: 2022
Type: conference-paper
Abstract: Transdermal drug delivery is a promising alternative to conventional drug delivery approaches, such as oral ingestion and hypodermic injection.Hypodermic injections are often painful, and oral ingestion of drugs requires the administration of doses higher than the needed to compensate for enzymatic degradation and poor absorption of drugs.Current transdermal drug-delivery platforms include microneedles, which resolve the pain aspect of conventional drug delivery approaches.However, microneedle patches are impractical as they are easily peeled off with motion and sweat.In this study, we propose soft injectables comprised of sutures that are loaded with drugs for painless and localized sustained drug delivery in the dermis layer of the skin.They stay in place during the course of delivery and are suitable for any skin type.
Institution: Tufts University
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4386823452