Year: 2022
Type: conference-paper
Abstract: We present a wearable system for in vivo serotonin (5-hydroxytryptamine, 5-HT) detection in crayfish hemolymph (i.e., blood).Surface-modified electrodes, with 4.9x improved 5-HT sensitivity, were integrated with a 3D-printed package to perform cyclic voltammetry (CV) by connecting to potentiostat electronics, enabling real-time data readout.The system was mounted on the crayfish dorsal carapace allowing electrode implantation into the heart for continuous in vivo 5-HT measurements (over 75 min) with a benchtop potentiostat.This system successfully monitored 5-HT dynamics in the targeted region with a high temporal resolution, providing a reliable platform for real-time neurochemical sensing.
Institution: University of Maryland, College Park
Language: English
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: bronze
Funder: National Science Foundation
OpenAlex ID: W4386823461