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FIGURE 5 from Pancreatic Ductal Adenocarcinoma Cells Regulate NLRP3 Activation to Generate a Tolerogenic Microenvironment

Year: 2023
Type: other
Abstract: NLRP3 activation mediates lympthocyte suppression. A, Tumor volume and weight in NCG mice fed standard (STD) or OL1177 (OLT) diet (n = 5/group). B, COX-2 levels measured by ELISAs in primary tumors of mice of mice fed STD and OLT-enriched diets. C, PGE2 levels measured by ELISAs in primary tumors of mice of mice fed STD and OLT-enriched diets. Data expressed as mean ± SEM. *, P < 0.05.
DOI: 10.1158/2767-9764.24168337.v1
Authors: Jesus Amo-Aparicio, Adrian Dominguez, Shaikh M. Atif, Alberto Dinarello, Tania Azam, Kibrom M. Alula, Miles Piper, Christopher H. Lieu, Robert W. Lentz, Alexis D. Leal, Stacey M. Bagby, Wells A. Messersmith, Sana D. Karam, Charles A. Dinarello, Todd M. Pitts, Carlo Marchetti
Language: English
Open Access status: gold
OpenAlex ID: W4386887769
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