Work

Inflammation attenuating lncRNAs in diabetic cardiomyopathy

Year: 2023

Type: article

Abstract: Diabetic cardiomyopathy refers to cardiac structural and functional impairments associated with hyperglycemia and obesity in patients with cardiovascular disease. Clinical outcomes are significantly worst for cardiovascular patients with diabetes and obesity compared with non-diabetic patients. At the core of adverse cardiac remodeling in the diabetic heart are molecular and functional changes in cardiomyocytes that promote hypertrophy, fibrosis, and metabolic rewiring. Clinical management is generally limited to glycemic control, without addressing the underlying cause of cardiomyocytes impairment in patients with diabetes.

Source: Molecular Therapy — Nucleic Acids

DOI: 10.1016/j.omtn.2023.102029

Authors: Sadia Mohsin, Hong Wang, Mohsin Khan

Institution: Temple University

Language: English

Topic: Cardiac Fibrosis and Remodeling

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,900